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Identifying how senescent cells avoid apoptosis allows for the prospective design of anti-senescence compounds to address whether homeostasis can also be restored

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18,19 Because an estimated 1–2% of all O 2 utilized by mitochondria results in formation of O 2 -• , the higher the partial pressure of O 2 and the more active the mitochondria, the greater the production of O 2 -• and other highly reactive oxygen free radicals, such as singlet oxygen ( 1 O)